The materiality of human bodies at the smallest scales—genes, microbes, chemicals, hormones—is increasingly being understood as both responsive to broader environmental contexts and as a site where environments are manifested in health and well-being. Phenomena from epigenetics to the microbiome, from toxic stress to toxic pollution, are raising new questions among the scientific community. They point to indeterminacies in personal and social capacities that might be transmitted across generations and implicated in patterns of inequality. Indigenous, activist, and popular knowledges operate alongside and in various relationships to these shifts in scientific paradigms. From the Anthropocene to postgenomic science, a tidal shift in approaches to human (and nonhuman) bodies is making it untenable to consider health as an individual property limited to the space of one’s body or the time of one’s lifespan—or even as something wholly human. This series probes the relationship between changing bio-scientific ideas about bodies and the lived realities of bodies in contemporary societies.